Based on the resource-based theory, this paper develops a theoretical model to analyze how the integration of innovation network resources affects the innovation performance of manufacturing enterprises, as well as the mediating effect of dual innovation and the moderating role of environmental uncertainty. The empirical results show as follows: innovation network resource integration and dual innovation are conducive to improving the innovation performance of manufacturing enterprises; dual innovation plays a part of intermediary role in the relationship between innovation network resource integration and innovation performance; environmental uncertainty positively regulates the relationship between the integration of innovation network resources and exploratory innovation, and exploratory innovation and innovation performance, while it does not play a significant role in the innovation network resource integration, exploitation innovation and innovation performance.