Based on the location entropy index, the agglomeration pattern of strategic emerging industries in Beijing－Tianjin－Hebei region from 2012 to 2017 is described. Meanwhile, the spatial Durbin model is established by incorporating geospatial factors into the panel model to empirically test the spatial spillover effect of strategic emerging industries agglomeration on the economic growth of Beijing－Tianjin－Hebei region. Finally, the spatial spillover effect is decomposed by partial differential equation, and the influence of industrial agglomeration and other control variables on economic growth is analyzed. The results show that: first, both the agglomeration of strategic emerging industries and economic growth have "spatial autocorrelation" and "spatial spillover effect". Second, at the current stage, the "reflux effect" of strategic emerging industries agglomeration in Beijing－Tianjin－Hebei region is greater than its "diffusion effect", resulting in the overall negative effect of industrial agglomeration on economic growth, which plays a restraining role. Third, the strategic emerging industries in Beijing－Tianjin－Hebei region have weak collaborative agglomeration, and the misallocation of industrial resources and lack of collaborative sharing mechanism are obvious. Fourth, human capital, investment in fixed assets, technological innovation, foreign investment and other control variables have positive effects on economic growth, while urbanization and financial investment have negative effects on economic growth in the Beijing－Tianjin－Hebei region.