The positive influence of customer-centered orientation in the transformation of manufacturing service strategy has received wide attention in academia. However, in view of the choice of service strategy in different situations of manufacturing enterprises, what customer-centered orientation should be adopted to help manufacturing enterprises achieve successful performance in service strategy transformation has not attracted enough attention in previous studies. From the perspective of customer-centered orientation, this paper takes 208 manufacturing enterprises in East, Central and South China as research objects, and explores the impact of different customer-centered orientation on the performance of service-oriented strategic transformation of manufacturing enterprises under different service-oriented strategic choices. The results show that when the customer-centered orientation maintained by manufacturing enterprises is relatively suitable or matched with the specific service-oriented strategic nature of manufacturing enterprises, the positive impact of customer-centered orientation on enterprise performance is often more significant. That is to say, the selection or implementation of the specific service strategy of manufacturing enterprises will increase the probability of successful transformation or performance acquisition of the service strategy of manufacturing enterprises if the customer-centered orientation that matches or adapts to the nature of the enterprise service strategy type can be created within the organization.