This study uses CiteSpace to conduct a bibliometric analysis of existing research on the innovation ecosystem in the Web of Science database from 2001 to 2018. Based on the results of co-occurrence analysis of term words, we first systematically sort out the basic research of the innovation ecosystem. Secondly, this study tracks the latest literature and related citation analysis in this field from 2016 to 2018. Based on the results of literature co-citation analysis, we have summarized three major research fronts: "ecosystem" reflection and supplementation, system risk prediction and response, system member behavior and micro-governance mechanisms. Finally, the article aims at the shortcomings of existing research, and proposes suitable exploration directions for future research.