The research measures the efficiency of independent innovation in the national high-tech zone, improves the gravitation model, and establishes the spatial correlation network of the efficiency of independent innovation in the national high-tech zone. The characteristics of global network and individual network are analyzed by using social network analysis method.It is found that the west high-tech zone and the northeast high-tech zone have the highest efficiency of independent innovation, the middle high-tech zone has the medium efficiency of independent innovation, and the east high-tech zone has the lowest efficiency of independent innovation. The independent innovation efficiency of strategic emerging industries is the highest. Most high-tech zones belong to two-way spillover plate and net spillover plate, while pearl river delta high-tech zone belongs to net beneficiary plate. The spatial association network of independent innovation is typical of agglomerating subgroups. High-tech zones play different intermediary roles in the overall level and the internal level of the plate.