As the main support and core pursuit of urbanization, the relationship between land transfer and urbanization quality affects the sustainable development of cities. Taking the Yangtze River Economic Belt as an example, this paper constructs a comprehensive evaluation index system of land transfer and urbanization quality, and makes an empirical study on the spatial-temporal differences of the coupling coordination between the two by using the entropy method and the coupling coordination model, and the spatial manifestation of the coupling and coordination was made by using ArcGIS. The results show that: the coordination degree between land transfer and urbanization quality shows a trend of increasing first, then decreasing and then increasing. The coordination degree of the Yangtze River Economic Belt gradually increases from west to east, the coupling degree has no obvious distribution law, and the overall is in a high level coupling state. The difference between the degree of land transfer and the quality of urbanization has always existed among urban agglomerations, however the differences within urban agglomerations are gradually decreasing. From the perspective of coupling and coordinated development of land transfer and urbanization quality, this paper puts forward policy recommendations for achieving healthy and sustainable urban development.