With the spatial econometric model and panel threshold model, this paper uses the panel data of 2008~2017 from 31 provinces and municipalities to empirically analyze the influence of innovation talent elements agglomeration and innovation capital elements agglomeration on regional synergistic innovation,Sand the government’s regulating effect on the relationship. The study reveals that the agglomeration of innovation talent elements and capital elements has significantly positive influence on regional synergistic innovation,Sin which government’s control of positive regulation. Meanwhile, the government’s control has double thresholds. The regulating effect is very significant when the control is lower than the threshold value, weakening with the increase of control.