Based on the viewpoint of industrial agglomeration, this paper takes creative talents as the research object, explores the influence mechanism of innovation factors on innovation performance in cultural parks, explores the intermediary role of innovation environment, and tests the regulatory role of policy allocation. This paper establishes a mediating role model based on innovation factors and innovation performance of cultural industry parks, and conducts empirical analysis with questionnaire survey. The results show that: (1) innovation factors have a significant positive impact on innovation environment, but among the three dimensions of innovation factors, social network and personal growth have no significant impact on innovation performance; (2) information sharing and knowledge spillover dimensions of innovation factors and innovation performance are directly significant, while individual ability influences innovation output through the intermediary role of innovation environment; (3) policy allocation in innovation environment. The intermediary effect of innovation environment and innovation performance plays a positive regulatory role. The higher the degree of policy support, the greater the impact on innovation output. Therefore, the government should guide the establishment of innovation-oriented factor agglomeration, by creating a good innovation atmosphere, improving the social network structure, reducing regional innovation resistance, and then enhance the ability of cultural creativity to gather and spill over.