Frugal innovation has been paid more and more attention, but its realization path is seldom paid attention to. Based on the theory of design-driven innovation ,organizational learning and resource bricolage,a chain mediating model of design thinking affects enterprise''s frugal innovation is constructed. According to the survey data, the results show that design thinking not only has a significant positive impact on enterprise''s frugal innovation, but also has a mediating effect on enterprise''s frugal innovation through learning from failures and resource bricolage. In addition, learning from failures and resource bricolage play a chain mediating role in the relationship between design thinking and frugal innovation, that is, design thinking improves ability of resource bricolage by promoting learning from failures, and then affects enterprise''s frugal innovation. The research results explore the influencing factors and inducing mechanism of enterprise''s frugal innovation from the perspective of design thinking, and provide certain theoretical and practical guidance for organizational innovation management.