Different from Hidalgo et al. (2007) which construct a measure of industrial distance, and based on the natural conditions, human resources, material capital, science and technology, economic structure and regime which include 23 kinds of factor endowments, we construct the "distance" measure of all manufacturing industry. According to the distance, we draw the spatial distribution map of the industry, and then we use the Dijkstra algorithm to calculate the shortest path from 10 low-value industries upgrading to three high-value industries. The study found that resource-based industries to upgrade to high-value industries need experience more rounds, and sometimes there even are no paths upgrading to high-value industries. some of the intermediate industry has always appeared in the path from low-value industries upgrading to high-value industries. If the central and western provinces could approach these industries when they undertake eastern industries, their ways of industry development and upgrading is bound to become broader.