To analyze the factors which restrain the technology transfer efficiency in chinese key universities , the dynamic change of technology transfer efficiency in 91 China universities from 2007 to 2016 is calculated based on the stochastic frontier analysis, and the impact of external heterogeneous factors on the efficiency of technology transfer in regional markets and universities is explored. The results show that the demanding of the market has limited stimulation on the efficiency of technology transfer;. Excessive market demand may inhibit the improvement of technology transfer efficiency; The convergence of high-tech industries and the enhancement of the link with the market can highly improve technology transfer efficiency. In addition, research on the change pattern of technology transfer efficiency has demonstrated a significant difference in different subject structures and regions. Finally, corresponding policy recommendations are proposed for universities and governments to improve the efficiency of technology transfer based on the research conclusions.