District economy cooperation is the trend of international economic unification, through analyze the district cooperation and exchanges history, present condition of economic district, positive effect of Fukien and Nagasaki. Bring up measures to enhance the economy cooperation of Fukien and Nagasaki, such as to enhance the high layer come-and-go, to push forward the economic cooperation of agriculture, servicing business, ocean, etc. Together promote the economy development of Fukien and Nagasaki, it will benefit the people of Fukien and Nagasaki.