By using multi-dimensional data sources to construct cases and analyzing typical cases, it is found that transformation scientists are the driving force for the failure saving of biopharmaceutical innovation. The rescue process includes four main stages: value exposure, capacity absorption, path transformation and conventional innovation. The factors that play a key role in the rescue process are mainly lucky serendipities, specific social capital and integration ability, the innovation subject has the contingency adjustment function.On this basis, the process model of technological innovation failure rescue is refined, and the management enlightenment is put forward for enterprises to rescue technological innovation failure projects.