Taking binary learning as a mediating variable and slack resources as a moderating variable, the paper constructs a theoretical model which proves that organizational forgetting influence cross-boundary innovation, and puts forward corresponding hypotheses. Then the paper uses structure equation model, bootstrap analysis and multiple regression to verify hypotheses. The results show that: organizational forgetting have a positive effect on cross-boundary innovation; exploitative learning and exploratory learning play individual and continuous mediating roles on the relationship between organizational forgetting and cross-boundary innovation; slack resources plays a positive moderating role on the relationship between organizational forgetting and cross-boundary innovation.