Integration with digital economy is an important means to realize the transformation and upgrading of traditional manufacturing industry. How to stimulate the endogenous kinetic energy of the integration of traditional manufacturing industry and digital economy has attracted more and more attention from academic and political circles. Based on the configuration perspective and QCA research method, taking 172 listed mechanical manufacturing companies as samples, this paper explores the multiple concurrent and asymmetric complex causality of the integration of traditional manufacturing industry and digital economy. The results show that: (1) innovation strategy, obtaining subsidies, reducing labor costs, digital Inclusive Finance, digital talent agglomeration and digital infrastructure are not the necessary conditions for the integration of traditional manufacturing industry and digital economy; (2) the high integration power of traditional manufacturing industry and digital economy has two effective configurations: Government subsidy driven and innovation leading under the condition of complete exogenous factors; (3) The number and case coverage of non high fusion power configuration are much higher than that of high fusion power configuration.