In order to reveal a series of management problems and existing research hotspots encountered by enterprises in the process of pursuing digital innovation, and to clarify the development context and research trend of leadership and management in digital innovation, based on the research literature of SCI ( E ) and SSCI databases in the core database of Web of Science from 2003 to 2022. With the help of scientific knowledge mapping analysis method, a visualized scientific quantitative analysis of the research literature on leadership and management in digital innovation were discussed. The results show that the research hotspots mainly cover three themes : the planning and implementation of digital transformation strategy, the influence of transformational leadership and the realization of digital innovation. The evolution of hot spots has changed from the initial focus on the application and management of digital technology to the value promotion of digital technology by managers through guiding the new development of enterprises, and finally to the development of digital innovation reacting on leadership and management, which puts forward new requirements for enterprise leadership and management to better realize the digitization of enterprise management. The evolution path of hot spots has experienced four stages : theoretical construction, organizational change, transformation development and digital leadership. Platform management, digital leadership and digital innovation realization under the background of digital transformation or will become the future research direction.