The development of digital economy plays an important role in achieving high-quality and full employment, and promoting employment in the service industry is an important means to achieve high-quality and full employment. Based on the panel data of prefecture level cities from 2011 to 2019, this paper analyzes the impact of the digital economy on service industry employment, and further examines the industry heterogeneity and spatial effects of this impact. The results show that the digital economy is conducive to increasing employment in the service industry, and the same conclusion is reached by using the micro data of the China Labor-force Dynamic Survey; Digital economy mainly increases employment in the service industry by expanding the size of urban population and promoting the service of industrial structure; The impact of the digital economy on the employment of the service industry has industry heterogeneity, which has a positive impact on the employment of the circulation service industry, personal service industry and production service industry, but there are significant differences in the degree of impact, which has no significant impact on the employment of the public service industry; The digital economy has a spatial effect on the employment of the service industry, and the spatial effect also has industry heterogeneity.