With the in-depth development and wide application of digital technology, digital innovation has gradually become the key driving force for the high-quality development of intelligent manufacturing enterprises. From the perspective of technology affordance, 380 listed intelligent manufacturing companies from 2016 to 2021 was used to establishes a fixed effect model, which systematically explores the multidimensional impact of technology, behavior subject and context on digital innovation of intelligent manufacturing enterprises. It is found that: ① digital resources, chief information officers and regional digital economic environment provide strong support for digital innovation of intelligent manufacturing enterprises; ② the enabling effect of digital resources, chief information officers and their interaction in digital innovation plays a more significant role for state-owned and highly absorptive intelligent manufacturing enterprises; ③ the optimization of regional digital economic environment assists the chief information officers and information technology to maximize the effectiveness of digital innovation in the interaction.