Promoting the greening of production methods is a key way to achieve high-quality economic development and build a modern socialist country. Based on the connotation and extension of green production methods, a green production method indicator system for the Yangtze River Economic Belt covering three dimensions of green industrial layout, green production process and green manufacturing system and 26 indicators is constructed. The Fixed base range entropy weight method is applied to measure the green level of production methods as a quantitative indicator of its green production mode in the Yangtze River Economic Belt from 2015 to 2020, and kernel density estimation, spatial visualization analysis and coupling coordination degree analysis are used to conduct a comprehensive analysis of its spatial and temporal evolution characteristics and synergy effects. The study found that the greening level of production methods in 11 provinces (municipalities) in the Yangtze River Economic Belt achieved a relatively rapid increase between 2015 and 2020, showing an overall increase year by year, but the differences in the greening level of production methods among the provinces (municipalities) along the belt have gradually expanded. The level of greening of production methods in the Yangtze River Economic Belt shows a positive spatial correlation, but this spatial correlation gradually decreases between 2017 and 2020. There are obvious regional differences in the level of greening of production methods in the Yangtze River Economic Belt, showing a distribution pattern of "downstream areas > midstream areas > upstream areas". The synergy effect of the three dimensions of green industry layout, green production process and green manufacturing system in the green production mode of the Yangtze River Economic Belt is gradually increasing, but the overall synergy level is still low, with obvious regional differences, and the synergy capacity still needs to be improved.