Resistance to change plays a key role in the success or failure of organizational change, and most studies regard change resistance as a negative change reaction behavior. Recently, some scholars believe that resistance to change has not only negative side, but also positive side. However, there is no relevant measurement tool to represent the full connotation of resistance to change, which will affect the academic and practical circles?? comprehensive understanding of resistance to change. Based on grounded theory, the literature on resistance was combed to change and open interviews with enterprise workers was conducted, the connotation and structure of resistance to change in depth was exploved, and a resistance to change scale was developed. And through the content validity, structure validity and criterion validity of the resistance change scale, the measurement scale was revised and verified. The results show that resistance to change consists of two dimensions, individual orientation and organization orientation, with a total of seven items. In addition, further empirical research is conducted to test the differentiated impact of individual-oriented and organization-oriented resistance to change on turnover intention. It is clarified the connotation and structure of resistance to change and developed a measurement scale of change resistance, which provided a reference and measurement basis for expanding the theory of organizational change and condensing the behavior law of change response.